ReDisulphID

a tool for identifying drug-targetable redox-active disulphides

H-2 class II histocompatibility antigen, A-U alpha chain

Intramolecular
Cysteine 105 and cysteine 161
A redox-regulated disulphide may form within H-2 class II histocompatibility antigen, A-U alpha chain between cysteines 105 and 161 (107 and 163 respectively in this structure).

Details

Redox score ?
79
PDB code
2pxy
Structure name
crystal structures of immune receptor complexes
Structure deposition date
2007-05-14
Thiol separation (Å)
2
Half-sphere exposure sum ?
81
Minimum pKa ?
nan
% buried
nan
Peptide accession
P14438
Residue number A
105
Residue number B
161
Peptide name
H-2 class II histocompatibility antigen, A-U alpha chain

Ligandability

Cysteine 105 of H-2 class II histocompatibility antigen, A-U alpha chain

Cysteine 161 of H-2 class II histocompatibility antigen, A-U alpha chain

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